TABLE 1

Pitfalls in 123I-Ioflupane SPECT

Pitfall typeDescription
BiologicDopamine transporter density
Age
Sex
Body habitus
Ethnicity
Allelic variants
Medications competing with dopamine transporter
Striatal infarct
Brain tumors
Trauma
Surgery
TechnicalPatient motion
Patient position
Patient orientation
Equipment resolution
Collimator
Dose extravasation
Time after injection
Photopeak
Oversmoothing on filtration
Attenuation correction
Size and placement of regions of interest
  • Adapted from Morbelli et al. (13).