Causes of Reduced RBC Labeling Efficiency
Cause | Drug or process |
Oxidation of stannous ion | Hydralazine |
Heparin | |
Methyldopa | |
Decreased hematocrit | |
Inadequate reduction of 99mTc | Excess stannous chloride |
Insufficient stannous chloride | |
Formation of RBC antibodies | Methyldopa |
Penicillin | |
Quinidine | |
Immune disorders | |
Leukemia and lymphoma | |
Complex formation with 99mTc | Dextrose |
Decreased RBC labeling | Prazosin |
Digoxin | |
Propranolol | |
Mechanism unknown | Doxorubicin |
Iodinated contrast |
(Adapted from (4)).