TABLE 1

Key Patient Characteristics and Imaging Features

Characteristic	Patient 1	Patient 2	Patient 3
Histopathology	Poorly differentiated adenocarcinoma	Conventional adenocarcinoma	Conventional adenocarcinoma
Gleason score	4 + 4	4 + 3	4 + 5
National Comprehensive Cancer Network prognostic category	High risk	Intermediate risk	High risk
PSA (ng/mL)
Baseline	65.128	751	228.03
After ¹⁷⁷Lu-PSMA	33.062	1,761.25	44.54
⁶⁸Ga-PSMA-11 uptake (SUV_max)
Baseline	64.73	27.04	116.84
After ¹⁷⁷Lu-PSMA	28.02	36.65	83.6
¹⁸F-FDG uptake (SUV_max)
Baseline	8.38	22.88	8.4
After ¹⁷⁷Lu-PSMA	4.41	9.63	4.5
Metastatic pattern of urinary bladder	Direct extension from prostate	Direct extension from prostate	Multifocal metastatic lesions involving bladder wall, hematogenous
HU of prostate
Baseline	100	125	93
After ¹⁷⁷Lu-PSMA	70	108	67
HU of urinary bladder metastases
Baseline	96	116	70
After ¹⁷⁷Lu-PSMA	67	83	41
Outcome	Partial response	Progression and death	Partial response