TABLE 1

Patient Characteristics; Tumor Stage on FIGO, PET/CT, and PET/MRI; and Impact on Clinical Management

Patient no.Age (y)FIGO stagePET/CT stagePET/MRI stageImaging commentsChange in clinical management? (PET/CT vs. PET/MRI)
161IIB (involving vaginal fornix, with suspected parametrial involvement)IVB (T2A N0 M1)IVB (T2B N0 M1)M1, paraaortic LN, on both modalitiesNo (both IVB); concurrent chemotherapy with cisplatin, EBRT to pelvis, and interstitial brachytherapy
255IIB (extending into parametrium and upper third of vagina)IIIB (T2A N1 M0)IIIB (T2B N1 M0)MRI detection of parametrial involvement, T2BNo (both IIIB); concurrent chemotherapy with cisplatin, pelvic EBRT, and intracavitary brachytherapy
376IIB (involving parametrium, without sidewall involvement)IIA (T2A N0 M0)IIB (T2B N0 M0)MRI detection of parametrial involvement, T2BNo (IIA vs. IIB); concurrent chemotherapy with cisplatin, pelvic EBRT, and intracavitary brachytherapy
460IIB (involving upper third of vagina and parametrium)IB (T1B N0 M0)IIB (T2B N0 M0)MRI detection of parametrial involvement, T2BYes; radical hysterectomy with pelvic nodal dissection (IB) vs. concurrent chemotherapy with cisplatin, pelvic EBRT, and intracavitary brachytherapy (IIB)
549IIB (extending into right fornix and right parametrium)IB (T1B N0 M0)IIB (T2B N0 M0)MRI detection of parametrial involvement, T2BYes; radical hysterectomy with pelvic nodal dissection (IB) vs. concurrent chemotherapy with cisplatin, pelvic EBRT, and intracavitary brachytherapy (IIB)
636IIIB (involving parametrium with extension to pelvic sidewall)IIB (T2B N0* M0)IVB (T2B N0 M1)MRI detection of peritoneal involvement, M1Yes; concurrent chemotherapy with cisplatin, pelvic EBRT, and intracavitary brachytherapy (IIB) vs. interstitial brachytherapy (IVB)
  • * N0 (focal ureter activity falsely denoted as N1 on PET/CT).

  • EBRT = external-beam radiotherapy.