TABLE 4

Statistical Analysis for MC Data

Mean (min)SD (min)MSEHermes/FLTHermes/F121F121/FLT
StudyE (min)HermesFLTF121HermesFLTF121HermesFLTF121FPFPFP
Tmax 1–33.73.773.743.780.590.190.280.340.040.0810.13<0.001*4.55<0.001*2.230.017*
Tmax 4–64.03.93.954.080.600.290.500.360.080.244.34<0.001*1.480.152.930.002*
T1/2 LK 1–36.64.966.496.391.720.300.425.470.100.2132.62<0.001*16.87<0.001*1.930.11
T1/2 RK 1–36.25.446.216.290.820.210.251.200.040.0715.15<0.001*10.66<0.001*1.420.25
T1/2 LK 4–69.86.349.379.272.970.811.2820.220.801.8213.35<0.001*5.350.002*2.490.05
T1/2 RK 4–69.27.039.39.181.750.620.897.540.370.757.83<0.001*3.830.008*2.040.10
  • * Statistically significant under Holm–Bonferroni adjustment for multiple comparisons.

  • E = expected value from Table 1; MSE = mean squared error (Formula/N).

  • Mean, SD, and MSE are from expected value for studies 1–3 with clearance of 260 mL/min and studies 4–6 with clearance of 130 mL/min. Hermes/FLT, Hermes/F121, and F121/FLT are ratio of variance obtained with F test and associated P value. LK = left kidney; RK = right kidney.