Comparison Table Between 18F-NaF and 99mTc-MDP (1,17)
| Characteristic | 18F-NaF | 99mTc-MDP |
| Production | Cyclotron | Generator |
| Half-life | 109.7 min | 6 h |
| Photon energy | 511 keV | 140 keV |
| Spatial resolution | Higher (4–5 mm) | Lower |
| Critical organ | Urinary bladder | Bones |
| Typical dose | 185–370 MBq (5–10 mCi) | 740–1,100 MBq (20–30 mCi) |
| Injection to imaging time | 30–60 min | 3–4 h |
| Effective dose | 8.9 mSv (370 MBq [10 mCi]) | 5.3 mSv (925 MBq [25 mCi]) |