Clearance Fractions and Therapeutic Doses Calculated by Cumulative-Activity Method and Residence-Time Method
Clearance fraction | Calculated therapeutic dose | |||
Patient no. | Fast component (%) | Slow component (%) | Cumulative-activity method (mCi) | Residence-time method (mCi) |
1 | 23.4 | 76.6 | 83.66 | 75.66 |
2* | 93.15 | 93.2 | ||
3 | 81 | 19 | 88.94 | 71.75 |
4 | 58.5 | 41.5 | 93.42 | 92.46 |
5* | 98.42 | 93.95 | ||
6* | 116.6 | 108.72 | ||
7 | 34.9 | 65.1 | 99.93 | 80.99 |
8 | 22.7 | 77.3 | 100.47 | 82.68 |
9* | 99.74 | 93.89 | ||
10 | 65 | 35 | 135.00 | 120.82 |
11 | 30.9 | 69.1 | 103.66 | 83.80 |
12 | 53.2 | 46.8 | 116.53 | 90.82 |
13 | 79 | 21 | 171.09 | 167.85 |
↵* Single component.