Differences Between Imaging Protocols for 18F-Fluciclovine PET/CT and 18F-FDG PET/CT
| Parameter | 18F-fluciclovine PET/CT | 18F-FDG PET/CT |
| Patient preparation | Ask patients to fast for at least 4 h, including water restriction | Ask patients to fast for at least 4 h, with no water restriction |
| Ask patients not to void for 1 h before 18F-fluciclovine injection and imaging | Ask patients to void immediately before imaging starts | |
| Injection site | Right arm | Right or left arm (if applicable, arm contralateral to cancer side) |
| Image acquisition | Start PET imaging 4 min after injection | Start PET imaging 30–90 min after injection |
| Image caudocranially, from mid thighs to skull base | Image craniocaudally (field of image is cancer-specific) |