Differences Between Imaging Protocols for 18F-Fluciclovine PET/CT and 18F-FDG PET/CT

Parameter18F-fluciclovine PET/CT18F-FDG PET/CT
Patient preparationAsk patients to fast for at least 4 h, including water restrictionAsk patients to fast for at least 4 h, with no water restriction
Ask patients not to void for 1 h before 18F-fluciclovine injection and imagingAsk patients to void immediately before imaging starts
Injection siteRight armRight or left arm (if applicable, arm contralateral to cancer side)
Image acquisitionStart PET imaging 4 min after injectionStart PET imaging 30–90 min after injection
Image caudocranially, from mid thighs to skull baseImage craniocaudally (field of image is cancer-specific)