Comparison of Key Properties of Main Gadolinium Contrast Agents
| Contrast agent | Structure | Ionicity | Clearance T0.5 (h) | Osmolality (mOsm/kg water) | Viscosity at 37°C (cP) | T1 relaxivity (L/mmol-s) |
| Gadopentetate dimeglumine | Linear | Ionic | 1.6 | 1,960 | 2.9 | 4.1 |
| Gadoteridol | Macrocyclic | Nonionic | 1.57 | 630 | 1.3 | 4.1 |
| Gadodiamide | Linear | Nonionic | 1.3 | 789 | 1.4 | 4.3 |
| Gadoversetamide | Linear | Nonionic | 1.73 | 1,110 | 2.0 | 5.2 |
| Gadobenate dimeglumine | Linear | Ionic | 1.2–2 | 1,970 | 5.3 | 6.3 |
| Gadoterate | Macrocyclic | Ionic | 1.6 | 1,350 | 2.4 | 3.6 |
| Gadobutrol | Macrocyclic | Nonionic | 1.81 | 1,603 | 5.0 | 5.2 |
| Gadoxetate | Linear | Ionic | 0.93 | 688 | 1.2 | 6.9 |
| Gadofosveset | Linear | Ionic | 1,110 | 3.0 | 19 | |
| Blood | 290 | 1.5–2 |
With exception of gadoxetate, dose is 0.1 mmol/kg. Gadoxetate dose is 0.025 mmol/kg (27,29,31).