Medical oncology member | Communicates with nuclear medicine team on eligible patients | Workflow training |
| Enters orders in electronic health record for 177Lu-DOTATATE procedure and required medications | Eligibility training |
| Evaluates patients within week before each 177Lu-DOTATATE treatment and monitors for adverse events afterward | |
Pharmacist | Provides antiemetics, amino acids, and posttreatment long-acting somatostatin analog on treatment day | Workflow training |
Radiation safety officer | Provides 177Lu radiation safety training to nuclear medicine staff | Workflow training |
| Prepares treatment room and restroom with contamination control measures; provides radiologic survey support as needed | |
| Collects residual or unused doses and associated contaminated materials and manages inventory of those items for ultimate disposal | |
| Reviews each record of therapeutic administration | |
| Develops and maintains basis for release of patients after treatment | |
Nuclear medicine nurse | Checks electronic medical record on day before treatment to ensure medication orders have been entered correctly and sends them to pharmacy on treatment day | Workflow and radiation safety, including patient care and waste disposal |
| Places intravenous catheter in patient (can also be done by nuclear medicine technologist) | Medication management and Alaris pump |
| Administers antiemetics, amino acids, and long-acting somatostatin analog | |
| Monitors for adverse events during amino acid infusion, checks blood pressure and pulse just before and after 177Lu-DOTATATE infusion, and ensures that patient voids before and hourly after infusion | |
Nuclear medicine physician | Gets informed consent from patients and reviews radiation safety instructions with patient | Workflow and radiation safety |
| Assays 177Lu-DOTATATE dose in dose calibrator, assesses intravenous line patency, performs time-out before infusion, and gives infusion | Graseby pump |
| Assesses status and discharges patient from nuclear medicine department | |
Nuclear medicine technologist | Orders, receives, inspects, and prepares 177Lu-DOTATATE dose for administration; prepares patient for treatment (can also be done by nurse) | Workflow and radiation safety, including dose preparation and waste disposal |
| Surveys restroom floor and path to treatment area with Geiger counter; contacts radiation safety officer and restricts access to contaminated areas if found | Graseby pump and 177Lu-DOTATATE dose preparation |
| Prints patient dose administration card; measures exposure 1 m from patient, and confirms that level is below that established by radiation safety officer once all administrations are complete | |