Comparison of Performance of Equations for eGFR to 2 99mTc-DTPA Reference Methods for mGFR in Patients with Hepatic Cirrhosis
Reference GFR method | |||
Estimating equation | Parameter | UV/P DTPA mGFR | Plasma DTPA mGFR |
MDRD | Accuracy p10 | 29.63% | 35.19% |
Accuracy p20 | 48.15% | 68.52% | |
Accuracy p30 | 57.41% | 88.89% | |
Precision | 16.45 | 17.50 | |
Mean bias | −6.23 (−14.70 to 2.23) | 1.54 (−4.73 to 7.86) | |
Mean percentage bias | 19.32% | 2.53% | |
Correlation | 0.72 (0.56–0.83) | 0.69 (0.52–0.81) | |
CKD-EPI (SCr) | Accuracy p10 | 20.37% | 35.19% |
Accuracy p20 | 38.89% | 64.81% | |
Accuracy p30 | 55.56% | 83.33% | |
Precision | 17.28 | 15.06 | |
Mean bias | −10.46 (−20.22 to −0.70) | −2.69 (−8.93 to 3.55) | |
Mean percentage bias | 26.03% | 17.90% | |
Correlation | 0.57 (0.36–0.73) | 0.70 (0.53–0.81) | |
CKD-EPI (CysC) | Accuracy p10 | 22.22% | 31.48% |
Accuracy p20 | 44.44% | 61.11% | |
Accuracy p30 | 59.26% | 77.78% | |
Precision | 25.55 | 19.59 | |
Mean bias | −6.61 (−16.73 to 3.50) | 1.16 (−5.13 to 7.44) | |
Mean percentage bias | 34.84% | 19.51% | |
Correlation | 0.53 (0.30–0.70) | 0.71 (0.54–0.82) | |
CKD-EPI (CysC+SCr) | Accuracy p10 | 16.67% | 42.59% |
Accuracy p20 | 50.00% | 75.93% | |
Accuracy p30 | 61.11% | 85.19% | |
Precision | 18.13 | 14.18 | |
Mean bias | −8.63 (−17.99 to 0.74) | −0.85 (−6.25 to 4.54) | |
Mean percentage bias | 23.21% | 15.04% | |
Correlation | 0.62 (0.42–0.76) | 0.79 (0.66–0.87) |
Data in parentheses are 95% confidence intervals.