Diagnostic Criteria for Esophageal Transit Scintigraphy (11)

ConditionVisual bolus transit analysis from dynamic displayEsophageal transit timeEsophageal retention at 10 min
NormalNormal aboral bolus transit through upper, middle, and lower thirds of esophagus with normal relaxation of lower esophageal sphincter<14 s<18%
Nonspecific esophageal motility disorderAny localized abnormal retrograde‚Äďantegrade bolus movement (normal movement is mild, transient, and retrograde in distal esophagus before relaxation of lower esophageal sphincter, which clears rapidly)>14 s>18%
Isolated lower esophageal sphincter dysfunctionNormal bolus transit in upper and middle esophagus with delayed transit localized at gastroesophageal junction>14 sUsually <18%; may see mild retention of <30%
SclerodermaMarked delay in bolus transit, typically localized to distal esophagus>30 s>30%, with marked improvement when upright
Diffuse esophageal spasmRepetitive retrograde‚Äďantegrade contractions throughout esophagus>14 sNormal or mild retention, <30%
AchalasiaMarked delay in bolus transit throughout esophagus (may progress normally in upper esophagus from oropharyngeal propulsion)>30 s>50%, with no improvement when upright