Radiotracers for Perfusion and Molecular Imaging of PVD
Modality | Perfusion/blood flow | Angiogenesis | Atherosclerosis |
SPECT | 201Tl (7,21,24–26) | 99mTc-NC100692 (47,48) | |
99mTc-sestamibi (27,29,31) | 111In-VEGF121 (45) | ||
99mTc-pyrophosphate (76) | 125I-c(RGD(I)yV) (77) | ||
99mTc-tetrofosmin | |||
PET | 15O-water (32,33,36,40) | 76Br-nanoprobe (50) | 18F-FDG (58–62) |
C15O2 (35) | 68Ga-NOTA-RGD (49) | 18F-sodium fluoride (66) | |
15O2 (35,36) | 64Cu-DOTA-CANF-comb (52) | 11C-acetate (67) | |
13N-ammonia (34) | 64Cu-DOTA-VEGF121 (46) | 64Cu-DOTA-CANF (65) |
CANF = C-type atrial natriuretic factor.