TABLE 1

Summary of Synthesis Data

Specific activity
TracerDecay-corrected radiochemical yield (%)Synthesis duration (min)*GBq/μmolCi/μmol
d-18F-FAC31 ± 4 (n = 11)16337–441.0–1.2
l-18F-FMAU49 ± 7 (n = 7)170100–1702.7–4.6
d-18F-FEAU (3-reactor)39 ± 4 (n = 3)1803.8–5.10.10–0.14
d-18F-FEAU (1-reactor)28 ± 4 (n = 3)1407.4–200.20–0.53
18F-FDG70 ± 9 (n = 3)38NA
18F-FLT69 ± 3 (n = 5)6567–4811.8–13
18F-fallypride66 ± 8 (n = 6)5615–780.4–2.1
18F-FHBG11 ± 2 (n = 3)8792–1892.5–5.1
18F-SFB69 ± 8 (n = 6)78631.7
  • * Synthesis duration was defined from start of synthesis to end of synthesis, including purification but not including reformulation.

  • Range of specific activities measured at time of injection into analytic HPLC.

  • Starting activity was lower than average and ranged from 1.3 to 1.9 GBq (35–50 mCi).

  • NA = not applicable.

  • Radiochemical yields are mean ± SD.