Summary of Synthesis Data
Specific activity† | ||||
Tracer | Decay-corrected radiochemical yield (%) | Synthesis duration (min)* | GBq/μmol | Ci/μmol |
d-18F-FAC | 31 ± 4 (n = 11) | 163 | 37–44 | 1.0–1.2 |
l-18F-FMAU | 49 ± 7 (n = 7) | 170 | 100–170 | 2.7–4.6 |
d-18F-FEAU (3-reactor) | 39 ± 4 (n = 3) | 180 | 3.8–5.1‡ | 0.10–0.14 |
d-18F-FEAU (1-reactor) | 28 ± 4 (n = 3) | 140 | 7.4–20‡ | 0.20–0.53 |
18F-FDG | 70 ± 9 (n = 3) | 38 | NA | |
18F-FLT | 69 ± 3 (n = 5) | 65 | 67–481 | 1.8–13 |
18F-fallypride | 66 ± 8 (n = 6) | 56 | 15–78‡ | 0.4–2.1 |
18F-FHBG | 11 ± 2 (n = 3) | 87 | 92–189 | 2.5–5.1 |
18F-SFB | 69 ± 8 (n = 6) | 78 | 63 | 1.7 |
↵* Synthesis duration was defined from start of synthesis to end of synthesis, including purification but not including reformulation.
↵† Range of specific activities measured at time of injection into analytic HPLC.
↵‡ Starting activity was lower than average and ranged from 1.3 to 1.9 GBq (35–50 mCi).
NA = not applicable.
Radiochemical yields are mean ± SD.