TABLE 1

Demographic and Clinical Parameters in the 10 Patients of the Study Population

ParameterData
Median age (y)68.5 (range, 52–78)
Mean duration of cancer (mo)30 (range, 3–120)
Type of cancer (n)
 Lung4
 Prostate3
 Breast2
 Esophagus1
Prior radiotherapy (n)6 (60%)
Median time since last radiotherapy (mo)8 (range, 4–10)
Prior chemotherapy (n)4 (40%)
Median time since last chemotherapy (mo)18 (range, 2–34)
Prior radionuclide therapy (n)6 (60%)
Median time since last radionuclide therapy (mo)8 (range, 5–27)
Median baseline scores
 Skeleton-based pain8.44 (range, 7.2–9.8)
 Mobility2.99 (range, 2–4)
 Karnofsky performance45 (range, 40–50)
Median 4-wk scores
 Skeleton-based pain5.73 (range, 4.8–6.9)
 Mobility1.3 (range, 1–2)
 Karnofsky performance69 (range, 60–80)
Median 8-wk skeleton-based pain score3.82 (range, 3.3–4.8)
Median 12-wk skeleton-based pain score1.71 (range, 1.2–2.2)