The Effects of Monotherapy or Polytherapy on BMD
Region | Therapy | n | Mean | SD | 95% CI |
Lumbar spine | Polytherapy | 52 | 0.933 | 0.188 | 0.881–0.985 |
Carbamazepine monotherapy | 33 | 0.848* | 0.213 | 0.772–0.924 | |
Valproate monotherapy | 22 | 0.917 | 0.231 | 0.814–1.019 | |
Control | 38 | 1.0289 | 0.131 | 0.986–1.072 | |
Ward triangle | Polytherapy | 52 | 0.792 | 0.307 | 0.706–0.877 |
Carbamazepine monotherapy | 33 | 0.744 | 0.394 | 0.604–0.884 | |
Valproate monotherapy | 22 | 0.781 | 0.407 | 0.601–0.962 | |
Control | 38 | 0.873 | 0.254 | 0.79–0.957 | |
Greater trochanter | Polytherapy | 52 | 0.708 | 0.140 | 0.669–0.747 |
Carbamazepine monotherapy | 33 | 0.656 | 0.134 | 0.608–0.703 | |
Valproate monotherapy | 22 | 0.731 | 0.133 | 0.671–0.79 | |
Control | 38 | 0.729 | 0.119 | 0.69–0.769 | |
Femoral neck | Polytherapy | 52 | 0.938 | 0.1507 | 0.896–0.98 |
Carbamazepine monotherapy | 33 | 0.887** | 0.174 | 0.825–0.949 | |
Valproate monotherapy | 22 | 0.974 | 0.163 | 0.901–1.046 | |
Control | 38 | 1.004 | 0.102 | 0.971–1.038 | |
Total hip | Polytherapy | 52 | 0.813 | 0.161 | 0.768–0.857 |
Carbamazepine monotherapy | 33 | 0.762 | 0.213 | 0.686–0.838 | |
Valproate monotherapy | 22 | 0.828 | 0.217 | 0.732–0.925 | |
Control | 38 | 0.869 | 0.141 | 0.823–0.915 |
↵* P < 0.01 compared with control.
CI = confidence interval.