TABLE 1

Properties of Ideal Diagnostic Radiopharmaceutical for Imaging

 Properties Notes 1. Easy availability Be readily available at low cost 2. Particle emission Diagnostic purpose: be a pure γ-emitter—that is, have no particle emission such as α and β because these contribute radiation dose to patient without providing diagnostic information Therapeutic purpose: have particle emission such as α and β because these are useful for damaging abnormal cells 3. High target–to–nontarget activity ratio Provide maximum efficacy in diagnosis (therapy), and minimize radiation dose to patient 4. Proper metabolic activity Possess proper metabolic activity—that is, follow or be trapped in metabolic process of interest