TABLE 1

Distribution of Patients and Results

Study no.	Patient no.	Cancer history	Age (y)	Sex	Previous treatment	Location of pathology on CT scan	Bladder wall thickness	PET (+) pelvis	PET (+) other location	PET (+) bladder	PET (+) total	Final disease status	Classification of pelvis	Overall classification
1	1	Cervix (A)	54	F	Surgery plus radiotherapy	Pelvis	Diffuse	Cervix	No	No	Yes	Recurrence^*	True-positive	True-positive
2	2	Testicle	76	M	Surgery	Pelvis	Posterior lateral wall	Spermatic cordon	No	No	Yes	Complete remission	False-positive	False-positive
3	3	Bladder	72	M	TUR	Pelvis	Posterior lateral plus lymphadenopathies	Prostate	No	No	Yes	Complete remission^*	False-positive	False-positive
4	4	Cervix (A)	50	F	Surgery plus radiotherapy	—	—	No	No	No	No	Complete remission	True-negative	True-negative
5	5	Bladder (A)	44	M	TUR plus radiotherapy	Pulmonary nodules plus pelvis	Posterior wall	No	Mediastinum	No	Yes	Recurrence	True-negative	True-positive
6	6	Bladder (A)	78	F	TUR	Pulmonary nodules plus pelvis	Diffuse	Bladder	No	Yes	Yes	Recurrence^*	True-positive	True-positive
7	7	Prostate and bladder (A)	67	M	TUR plus radiotherapy	Pulmonary nodules plus pelvis	Diffuse	No	No	No	No	Complete remission	True-negative	True-negative
8	8	Rectal (A)	56	F	Surgery, chemotherapy, and radiotherapy	Renal (?)	No	Presacrum	No	Yes (false-positive)	Yes	Recurrence^*	True-positive	True-positive
9	9	Uterus (A)	54	F	Surgery, radiotherapy, and chemotherapy	Pelvis (ascitis)	No	No	No	No	Yes	Complete remission	True-negative	False-positive
10	10	Bladder and lung	76	M	Surgery plus intrabladder chemotherapy	Lung mass	No	No	Lung	No	Yes	Surgery	True-negative	True-positive
11	11	Bladder (A)	76	M	TUR, chemotherapy, and radiotherapy	Pelvis	Right wall	No	No	No	No	Complete remission	True-negative	True-negative
12	12	Cervix (A)	75	F	Surgery, chemotherapy, and radiotherapy	Pelvis (within the bladder)	No	Cervix–vagina	No	Yes	Yes	Recurrence^*	True-positive	True-positive
13	13	Cervix	69	F	Surgery	Pelvis (vagina)	No	Vagina	No	No	Yes	Recurrence^*	True-positive	True-positive
14	14	Gastric	64	F	Surgery	Pelvis	Anterior–superior wall	No	No	No	No	Complete remission	True-negative	True-negative
15	15	Cervix (A)	71	F	Surgery, radiotherapy, and chemotherapy	Pelvis (cervix)	No	Cervix	Pulmonary solitary nodule	No	Yes	Complete remission^*	False-positive	False-positive
16	16	Prostate	70	M	Radiotherapy	—	—	No	Bone chemotherapy	No	Yes	Recurrence	True-negative	True-positive
17	17	Bladder plus urothelial	66	M	TUR plus nephroureterectomy	No	No	No	No	No	No	Complete remission	True-negative	True-negative
18	18	Anal (A)	67	F	Chemotherapy plus radiotherapy	Pelvis (anal nodule)	No	No	No	No	No	Complete remission	True-negative	True-negative
19	15	Cervix (scan 2)			Surgery, radiotherapy, and chemotherapy	PET/CT	No	No	Pulmonary solitary nodule ↓	No	No	Complete remission	True-negative	True-negative
20	19	Renal plus bladder (A)	59	M	TUR	—	—	No	No	No	No	Complete remission^*	True-negative	True-negative
21	20	Cervix (A)	41	F	Chemotherapy plus radiotherapy	Pelvis: MRI (fibrothecoma)	No	No	No	No	No	Complete remission	True-negative	True-negative
22	21	Bladder (A)	80	M	Chemotherapy plus radiotherapy	Pelvis	Diffuse plus lymphadenopathies	Prostate	Suprarenal, lymphadenopathies	Yes	Yes	Recurrence	True-positive	True-positive
23	22	Bladder and lung	74	M	UR	Lung mass	No	Bladder	Lung	Yes	Yes	Staging^*	True-positive	True-positive
24	5	Bladder (scan 2)			TUR plus radiotherapy	—	—	No	No	No	No	Complete remission	True-negative	True-negative
25	5	Bladder (scan 3)			TUR plus radiotherapy	—	—	No	No	No	No	Complete remission	True-negative	True-negative
26	1	Cervix (scan 2)			Chemotherapy plus radiotherapy	—	—	Pelvic masses	No	No	Yes	Progression	True-positive	True-positive
27	1	Cervix (scan 3)			Surgery plus radiotherapy	Pelvis (masses)	No	Pelvic masses	No	No	Yes	Recurrence	True-positive	True-positive
28	23	Ovarian mass	64	F	—^†	Pelvis (ovarian mass)	No	No	No	No	No	Staging^*	True-negative	True-negative
29	24	Sigmoid colon IV (A)	73	F	Surgery plus chemotherapy	Pelvis (vaginal mass)	No	Vagina	Lymph node	Yes (false-positive)	Yes	Staging^*	True-positive	True-positive
30	25	Bladder	79	F	TUR	Pelvis	Anterior wall	Yes	No	Yes	Yes	Recurrence	True-positive	True-positive
31	26	Colon IV (A)	48	F	Surgery plus chemotherapy	Liver	No	No	No	No	Yes	Recurrence	True-negative	True-positive
32	27	Bladder	50	M	Partial resection^‡	—	—	No	No	No	No	Complete remission	True-negative	True-negative
33	28	Cervix	55	F	Chemotherapy plus radiotherapy	—	—	No	No	No	No	Complete remission	True-negative	True-negative
34	29	Urothelial (A)	63	F	Nephroureterectomy plus chemotherapy	Pelvis	Diffuse	Ureter–bladder junction	Suprarenal	Yes	Yes	Recurrence^*	True-positive	True-positive
35	30	Ovarian IV (A)	44	F	Surgery plus chemotherapy	Pelvis (pelvic mass)	—	Pelvic mass	Lymph node	No	Yes	Recurrence	True-positive	True-positive
36	31	Rectal (A)	67	F	Surgery	Liver	—	No	Liver plus lymph node	No	Yes	Recurrence	True-negative	True-positive
37	32	Uterus	56	F	Surgery	—	—	Cervix	No	No	Yes	Complete remission^*	False-positive	False-positive
38	33	Rectal (A)	76	F	Surgery, chemotherapy, and radiotherapy	Pulmonary nodules	—	No	Lung	No	Yes	Recurrence	True-negative	True-positive
39	34	Uterus (A)	73	F	Surgery	—	—	No	No	No	No	Complete remission	True-negative	True-negative
40	35	Bladder and lung	81	M	—^†	Lung mass	—	Bladder	Lung	Yes	Yes	Staging^*	True-positive	True-positive
41	36	Bladder	76	M	Surgery, radiotherapy, and chemotherapy	Pelvis	Diffuse	Bladder	No	Yes (false-positive)	Yes	Hemorrhagic cystitis	False-positive	False-positive
42	37	Unknown origin tumor	47	M	—^†	Lung nodule plus lymphadenopathies	No	No	Lung plus lymph node	No	Yes	Staging	True-negative	True-positive
43	38	Rectal (A)		M	Surgery, chemotherapy, and radiotherapy	—	—	No	No	No	No	Complete remission	True-negative	True-negative

↵* Histopathologic confirmation.
↵† No previous chemotherapy.
↵‡ Partial resection, without clean surgical margins.
A = locally advanced; PET (+): PET-positive suggestion of malignancy; TUR: transurethral resection of bladder malignancy; ↓ = decreased in size and metabolism; IV = distant metastases.