TABLE 4

Intrasubject Variability of Various DAT Radioligands for SPECT

				Intrasubject variability^*
Study	Ligand	Total patients (n)	Delineation	Healthy volunteers	Patients	Reliability ICC
Ziebell et al. (17)	PE2I	7	MD HC	4.1 ± 3.2		0.96
Seibyl et al. (20)	β-CIT	7	Template WS	12.8 ± 8.9^†		0.82
Booij et al. (18)	FP-CIT	6	Template HC	7.3 ± 3.2		0.92^†
Tsuchida et al. (21)	FP-CIT	10	Template HC	11.1 ± 10.4		0.59
Pirker et al. (31)	β-CIT	9	MD HC	8.2 ± 7.2		0.70
Ziebell et al., current study	PE2I	8	MD HC		11.9 ± 10.0	0.88
Seibyl et al. (20)	β-CIT	7	Template WS		16.8 ± 13.3^†	0.82
Booij et al. (18)	FP-CIT	6	Template HC		7.9 ± 6.9	0.72^†
Tsuchida et al. (21)	FP-CIT	6	Template HC		7.8 ± 8.9	0.95
Hwang et al. (19)	Trodat	20	MD HC		10.2 ± 6.2	0.95

↵* Mean outcome for either BP_ND or SBR (±SD).
↵† Data extracted from publication.
ICC = intraclass correlation coefficient; HC = high-count slides; WS = whole striatum.