TABLE 1.

Definitions of Common Pharmacologic Terms

TermDefinition
AgonistA molecule that binds to a receptor and elicits a response by the cell
AntagonistA molecule that binds to a receptor, but rather than causing a response, blocks the binding of an agonist, so preventing the response
AffinityThe tightness with which an agonist/antagonist binds to a receptor (described using the dissociation constant)
SelectivityActivity of an agonist against a limited number of receptors