TABLE 1

Characteristics of Stress Ischemic Endpoints

PerfusionWall motion
Initial event in the ischemic cascadeFollows induced perfusion abnormality
Does not require ischemiaRequires ischemia
Specific indicator of ischemia or ischemic potentialNonspecific indicator of ischemia
Not significantly affected by loading conditionsAffected by loading conditions
Not significantly affected by resting wall motion abnormalitiesAffected by resting wall motion abnormalities
Not generally affected by conduction abnormalitiesAffected by conduction abnormalities
  • Adapted from (3).