Formulation of 99mTc-Radiopharmaceuticals
| Kit | Ingredients | pH | Imaging |
|---|---|---|---|
| Diisopropyl iminodiacetic acid | Diisopropyl iminodiacetic acid (20.0 mg), SnCl2·2H2O (0.2 mg) | ∼5.5 | Hepatobiliary |
| DMSA (III) | DMSA (1.0 mg), SnCl2·2H2O (0.60 mg), ascorbic acid (0.70 mg), inositol (50 mg) | ∼2.2 | Kidney |
| Diethylenetriaminepentaacetic acid | Diethylenetriaminepentaacetic acid (10 mg), SnCl2·2H2O (0.4 mg) | ∼7 | Kidney/brain |
| Heptagluconate | Calcium heptagluconate (100 mg), SnCl2·2H2O (0.12 mg) | ∼6 | Kidney/brain |
| Mercaptoacetyltriglycine | Mercaptoacetyltriglycine (1 mg), SnCl2·2H2O (0.1 mg), calcium heptagluconate (20 mg), lactose (20 mg) | ∼4.25 | Kidney |
| Methylene diphosphonate | Methylene diphosphonate (7.5 mg), SnCl2·2H2O (0.36 mg), ascorbic acid (1.8 mg), NaCl (2.0 mg) | 5.8–6 | Bone |
| Phytate | Phytic acid (25.0 mg), SnCl2·2H2O (1.0 mg) | ∼6.8–7 | Liver/spleen |
| Pyrophosphate | Pyrophosphate (10 mg), SnCl2·2H2O (2.5 mg) | ∼6.5 | Red blood cell labeling, bone, heart infarct |
| Dextran | Dextran (50 mg), SnCl2·2H2O (0.013 mg) | 6 | Lymph |
| Sestamibi | Sestamibi (1 mg), SnCl2·2H2O (0.075 mg), L-cysteine (1 mg), sodium citrate (2.6 mg), mannitol (20 mg) | ∼5.4–5.9 | Heart |
| Ciprofloxacin | Ciprofloxacin (3.8 mg), SnCl2·2H2O (0.39 mg), NaCl (4.4 mg) | Infection | |
| Exametazime | d,l-exametazime (0.5 mg), SnCl2·2H2O (7.5 μg), NaCl (6.75 mg) | ∼10–11 | Brain |
| DMSA (V) | DMSA (1.8 mg), SnCl2·2H2O (1.12 mg) | 8.5 | Medullary thyroid carcinoma |
| Na99mTcO4 | 0.9% NaCl, Na99mTcO4 (nanogram levels) | 6–7 | Thyroid |