Clinical Characteristics, Laboratory Values, and BMD Values of the 64 Patients, Stratified by Study Group
Feature | Group I (asymptomatic) | Group II (renal stone disease) | Group III (osteitis fibrosa cystica) | P | Reference range |
---|---|---|---|---|---|
Age (y) | 66.75 ± 0.63 | 55.8 ± 5.09 | 38.7 ± 4.38 | <0.01 | |
Sex ratio (M:F) | 1:4 | 2:7 | 11:10 | <0.01 | |
Serum calcium (mg/dL) | 10.98 ± 0.02 | 11.32 ± 0.17 | 13.35 ± 0.35 | <0.01 | 8.6–10.3 |
Serum phosphorus (mg/dL) | 2.79 ± 0.29 | 2.56 ± 0.47 | 1.99 ± 0.29 | <0.01 | 2.5–4.5 |
Serum PTH (pg/mL) | 135.45 ± 13.50 | 165.85 ± 15.06 | 579.6 ± 628.4 | <0.01 | 10–65 |
Serum 25-hydroxyvitamin D (ng/mL) | 26.97 ± 4.13 | 20.02 ± 0.56 | 15.91 ± 1.11 | <0.01 | 12–68 |
Urine NTx (nmol/mmol of creatinine) | 51.3 ± 6.4 | 154.1 ± 62.9 | 501.5 ± 201 | <0.05 | 50–60*, 15–120†, 6–65‡ |
Serum CTx (pg/mL) | 752.6 ± 496.3 | 727.3 ± 220.4 | 2,210.2 ± 375.4 | <0.05 | 50–450*, 90–680†, 70–480‡ |
BMD t score | |||||
Lumbar spine | −2.02 ± 0.15 | −1.83 ± 0.85 | −4.25 ± 0.24 | <0.01 | |
Femoral neck | −2.03 ± 0.28 | −1.81 ± 0.38 | −5.44 ± 1.37 | <0.01 | |
Distal radius | −2.23 ± 0.74 | −1.79 ± 0.04 | −5.33 ± 0.69 | <0.01 |