TABLE 1

Roles of Health Care Team Members During Administration of Tositumomab and ¹³¹I-Tositumomab Therapeutic Regimen

	Responsible Party
Role	Hematologist or oncologist	Radiation oncologist	Nuclear medicine physician	Nuclear medicine technologist	Radiation safety officer	Oncology nurse	Nuclear pharmacist	Hospital pharmacist	Medical physicist
Review radioactive material license					X		X		X
Identify and refer patients	X
Prescribe therapy		X	X
Educate patients	X	X	X	X	X	X	X	X	X
Place order with BSC							X
Report platelet counts for dose calculation	X
Prescribe thyroid block	X	X	X
Prescribe premedications	X
Receive packaging and prepare doses							X
Administer cold infusion	X	X		X		X
Monitor patient	X	X	X	X		X
Administer hot infusion		X	X	X
Report adverse events	X	X	X	X	X	X	X	X	X
Perform quality control procedures and acquire images				X
Calculate estimated dose (after second scan)		X	X	X					X
Calculate therapeutic dose		X	X	X					X
Send completed dosimetry worksheets to nuclear pharmacy				X					X
Report final dose calculation to BSC							X		X
Determine when patient can be released				X	X				X
Instruct patient regarding radiation safety precautions		X	X	X	X				X
Perform patient follow-up	X