TABLE 1

Health-Care Team for Ibritumomab Tiuxetan Therapy

Health-care professional	Roles and responsibilities
Hematologist/oncologist	• Patient identification and assessment (including pregnancy)
	• Patient education, consent
	• Prescription of rituximab dose
	• Patient follow-up and monitoring
Oncology nurse	• Coordination of patient scheduling with nuclear medicine, infusion clinic, and radiation oncology (as necessary)
	• Patient education
	• Patient monitoring before and after infusion
Nuclear medicine physician	• Review of pertinent patient information
	• Prescription of ¹¹¹In- and ⁹⁰Y-ibritumomab tiuxetan doses
	• Patient education and consent
	• Interpretation of whole-body images
	• Calculation and administration of therapy dose
	• Final procedure reporting and documentation
Nuclear medicine technologist/ nuclear radiopharmacist	• Interaction with oncology nurse; coordination of patient scheduling
	• Procurement and preparation of imaging and therapy doses
	• Safe and appropriate receipt, handling, administration, and disposal of radiopharmaceuticals
	• Patient education
	• Whole-body imaging of patients
Commercial radiopharmacist	• Receipt of orders; confirmation of patient dose
	• Order placement with supplier for cold kits and yttrium
	• Order placement for ¹¹¹In
	• Radiolabeling of drugs with ≥95% tagging efficiency
	• Delivery of unit dose to clinical site
Radiation safety officer	• Oversight of safe handling, administration, and disposal of radiopharmaceuticals according to state or federal guidelines
Utilization review/patient billing staff	• Confirmation of appropriate clinical indications
	• Acquisition of authorization from third-party payers
	• Follow-up (as necessary) on reimbursement issues
Radiation oncologist	• Review of pertinent patient information
	• Prescription of ⁹⁰Y-ibritumomab tiuxetan dose
	• Patient education
	• Calculation and administration of therapy dose
	• Final procedure reporting and documentation
Radiation oncology nurse	• Coordination of patient scheduling with nuclear medicine and infusion clinic
	• Patient education
	• Patient monitoring before and after infusion