TABLE 2.

Effect of Vincristine on the Biodistribution of Technetium-99m GHA in Mice

Organ% Uptake
Control (n = 15)Treated (n = 15)
Uterus0.0926 ± 0.00480.0253 ± 0.0040
Ovary0.0301 ± 0.00260.0105 ± 0.0013
Spleen0.0662 ± 0.01150.0235 ± 0.0024
Thymus0.0368 ± 0.00890.0111 ± 0.0019
Lymph node inguinal0.2038 ± 0.01100.0277 ± 0.0057
Lymph node mesenteric0.0832 ± 0.00550.0111 ± 0.0006
Kidney3.4316 ± 0.31051.2583 ± 0.2581
Heart0.1100 ± 0.00700.0655 ± 0.0137
Lung0.3639 ± 0.01410.3544 ± 0.0198
Liver0.4890 ± 0.03660.4738 ± 0.0537
Pancreas0.0172 ± 0.00230.0170 ± 0.0028
Stomach0.4384 ± 0.04770.4355 ± 0.0499
Thyroid0.0484 ± 0.01000.0493 ± 0.0087
Brain0.0483 ± 0.01330.0444 ± 0.0038
Bone0.0348 ± 0.00330.0340 ± 0.0029