TABLE 1.

Effect of Vincristine on the Biodistribution of Technetium-99m DMSA in Mice

Organ% Uptake
Control (n = 15)Treated (n = 15)
Lung0.9470 ± 0.20502.2530 ± 0.4946
Pancreas0.0443 ± 0.00740.0943 ± 0.0177
Heart0.4258 ± 0.06600.8077 ± 0.1318
Thyroid0.0479 ± 0.01430.0938 ± 0.0252
Brain0.0990 ± 0.02400.2529 ± 0.0676
Bone0.2198 ± 0.04000.4158 ± 0.0813
Lymph node inguinal0.0513 ± 0.01490.1163 ± 0.0307
Lymph node mesenteric0.0558 ± 0.01180.0888 ± 0.0263
Uterus0.1644 ± 0.00390.1654 ± 0.0020
Ovary0.1005 ± 0.02290.1017 ± 0.0231
Spleen0.2104 ± 0.02830.2230 ± 0.0351
Thymus0.0718 ± 0.01250.0841 ± 0.0200
Kidney7.5642 ± 0.63626.9787 ± 1.0892
Liver6.1344 ± 1.01506.5146 ± 0.6660
Stomach0.4325 ± 0.04260.4759 ± 0.1160