TABLE 3.

Duration of Breastfeeding Interruption (Studies Listed Alphabetically from M to S)

Study	Radiopharmaceutical	Administered dose	Institution guidelines, 2022	SNMMI/EANM procedure guideline (7)^*	Stabin and Breitz (2)	ICRP 106 (8)	Leide- Svegborn (1)^†	ACMUI (9)^‡
Meckel diverticulum	^99mTc-pertechnetate	555 MBq	12 h	12 h	4 h	12 h	12 h	24 h
Multigated acquisition	^99mTc-RBC modified in vivo	925 MBq	12 h	24 h	12 h	12 h	0	24 h
Myocardial perfusion (rest + stress)	^99mTc-tetrofosmin	1,184 MBq	4 h	4 h	NA	0	NA	24 h
Myocardial perfusion (rest + stress)	^99mTc-sestamibi	1,184 MBq	4 h	4 h	0	0	0	24 h
Myocardial perfusion	²⁰¹Tl-chloride	111 MBq	4 d	48 h	96 h	48 h	NA	4 d
Myocardial perfusion	⁸²Rb	1,100–1,850 MBq	—	NA	NA	NA	NA	0
Myocardial perfusion	¹³N-ammonia	370–740 MBq	—	NA	NA	0	NA	1 h
Sodium fluoride PET	¹⁸F-NaF	2.22 MBq/kg	0	NA	NA	NA	NA	4 h
Octreotide scan	¹¹¹In-octreotide	111 MBq	0	0	NA	0	NA	6 d
Parathyroid scan	^99mTc-sestamibi	740 MBq	4 h	0	0	0	NA	24 h
Parathyroid scan	^99mTc-tetrofosmin	185–925 MBq	—	0	NA	0	NA	24 h
Parathyroid scan (for dual phase)	^99mTc-pertechnetate	75–150 MBq	—	12 h	4 h	12 h	NA	24 h
Parathyroid scan (for dual tracer)	¹²³I-NaI and ^99mTc-sestamibi	7.5–20 and 740 MBq	4 d	3 wk	Stop	>3 wk	NA	3 d
R to L shunt	^99mTc-MAA	37 MBq	12 h	NA	NA	NA	NA	24 h
Renal cortical	^99mTc-gluceptate	296 MBq	4 h	NA	0	0	NA	24 h
Renal cortical	^99mTc-DMSA	111 MBq	4 h	NA	NA	0	NA	24 h
Renal function	^99mTc-MAG-3	260 MBq	4 h	4 h	0	0	0	24 h
Renal function	^99mTc-DTPA	370 MBq	4 h	12 h	0	0	0	24 h
Renal GFR	^99mTc-DTPA	37 MBq	4 h	NA	0	0	0	24 h
Salivary gland scan	^99mTc-pertechnetate	555 MBq	12 h	NA	4 h	12 h	12 h	24 h
SeHCAT scan	⁷⁵Se-tauroselcholic acid	0.37 MBq	>3 wk	NA	NA	>3 wk	NA	NA
Small-bowel and colon transit	^99mTc-SC	18.5–37 MBq	—	NA	0	0	NA	24 h

↵* Or publicly available guidance documents.
↵† Recommendation was based on both internal and external radiation exposure.
↵‡ Single 24-h interruption period is recommended for ^99mTc-labeled radiopharmaceuticals to simplify guidance.
RBC = red blood cell; 0 = no breastfeeding cessation is necessary; NA = data not available; — = not institutional procedure; DMSA = dimercaptosuccinic acid; MAG = mercaptoacetyltriglycine; DTPA = diethylenetriaminepentaacetic acid; SC = sulfur colloid.