Appropriate-Use Guidelines for 14 Clinical Scenarios (7) in Which 18F-FES PET Might Be Used
Scenario | Appropriateness of use | Score |
---|---|---|
Appropriate (scores of 7–9) | ||
8 | For assessing ER status when lesions are difficult to biopsy or biopsy is nondiagnostic | 8 |
9 | For considering second line of endocrine therapy after progression of metastatic disease | 8 |
10 | For considering endocrine therapy at initial diagnosis of metastatic disease | 8 |
14 | For detecting ER status when findings of other imaging tests are equivocal or suggestive | 8 |
May be appropriate (scores of 4–6) | ||
2 | For diagnosing malignancy of unknown primary when biopsy is nonfeasible or nondiagnostic | 5 |
5 | For routine staging of extraaxillary nodes and distant metastases | 5 |
6 | For staging invasive lobular carcinoma and low-grade invasive ductal carcinoma | 5 |
7 | For assessing ER status, in lieu of biopsy, in lesions that are easily accessible for biopsy | 5 |
13 | For detecting lesions in suspected or known recurrent or metastatic breast cancer | 5 |
Rarely appropriate (scores of 1–3) | ||
1 | For diagnosing primary breast cancer | 2 |
3 | For routine staging of primary tumor (T staging) | 1 |
4 | For routine staging of axillary nodes | 3 |
11 | For considering endocrine therapy at initial diagnosis of primary breast cancer | 1 |
12 | For measuring response to therapy | 1 |