TABLE 2.

Duration of Breastfeeding Interruption (Studies Beginning with L)

Study	Radiopharmaceutical	Administered dose (MBq)	Institution guidelines, 2022	SNMMI/EANM procedure guideline (7)^*	Stabin and Breitz (2)	ICRP 106 (8)	Leide- Svegborn (1)^†	ACMUI (9)^‡
Lacrimal gland	^99mTc-pertechnetate	7.4	0	NA	NA	NA	NA	NA
Liver, spleen	^99mTc-SC	200	4 h	NA	0	0	NA	24 h
Lung perfusion	^99mTc-MAA	74–185	12 h	NA	12 h	12 h	12 h	24 h
Lung ventilation	^99mTc-Technegas	18–37	0	NA	NA	0	NA	24 h
Lung ventilation	^99mTc-DTPA aerosol	20–40	—	NA	0	NA	NA	24 h
Lung ventilation	^99mTc-SC aerosol	20–40	—	0	NA	NA	NA	24 h
Lung ventilation	^81mKr gas	40–400	—	0	NA	0	NA	NA
Lung ventilation	¹³³Xe gas	200–750	—	0	NA	0	NA	NA
Lymphoscintigraphy	^99mTc-filtered SC	37	4 h	24 h	0	0	NA	24 h
Lymphoscintigraphy	^99mTc-unfiltered SC	185	4 h	24 h	0	0	NA	24 h
Lymphoscintigraphy	^99mTc-sulphide nanocolloid	3.7−370	—	24 h	NA	NA	NA	24 h
Lymphoscintigraphy	^99mTc-nanocolloidal albumin	3.7–370	—	24 h	NA	NA	NA	24 h
Lymphoscintigraphy	^99mTc-antimony trisulfide	3.7−370	—	24 h	NA	NA	NA	24 h
Lymphoscintigraphy	^99mTc-tilmanocept	3.7−370	—	24 h	NA	NA	NA	24 h
¹⁷⁷Lu-DOTATATE	¹⁷⁷Lu-oxodotreotide	3,700	Stop	2.5 mo	NA	NA	NA	Stop

↵* Or publicly available guidance documents.
↵† Recommendation was based on both internal and external radiation exposure.
↵‡ Single 24-h interruption period is recommended for ^99mTc-labeled radiopharmaceuticals to simplify guidance.
NA = data not available; 0 = no breastfeeding cessation is necessary; SC = sulfur colloid; DTPA = diethylenetriaminepentaacetic acid; — = not institutional procedure.