Summary of Literature on Hemodialysis in Patients with CKD After Radioiodine Therapy (n = 23)
| Study | Age (y) | Cancer | Dose (mCi)* | Time of dialysis | Conclusion of studies |
|---|---|---|---|---|---|
| Vermandel (10) | 67 | PTC | 60 | 42, 90 h | Use 30% reduction in dose for ablative and adjuvant treatments; for metastatic disease, dosimetry should be done; first dialysis 42 h after dose |
| 47 | PTC | 77, 82 | |||
| 63 | PTC | 61 | |||
| 63 | PTC | 50 | |||
| 29 | PTC | 60 | |||
| 71 | VC | 101 | |||
| Daumerie (11) | 42 | PTC | 25 in 2 sessions 6 mo apart | 2, 5, 7 d | Administer 25% of prescribed activity; first dialysis 24 h after dose |
| 62 | PTC | ||||
| 27 | PTC | ||||
| Jiménez (16) | 42 | PTC | 75 | Daily for 5 d | Use dosimetry to determine dose; dialysis every day for 5 d |
| 51 | PTC | 87 | |||
| 34 | PTC | 120 | |||
| Holst (9) | 40 | PTC | 98 | 2, 3, 4 d | Use 21%–28% of dose; dialysis at days 2 and 4 |
| Mello (12) | 42 | PTC | 100 | 41, 98 h | Use dosimetry to determine dose |
| Sinsakul (17) | 43 | PTC | 100 | 20 or 24 h | Perform dialysis 2–24 h after dose |
| 56 | PTC | 157 | |||
| Culpepper (14) | 56 | FTC | 129 | 24, 43, 66 h | None |
| Howard (8) | 34 | PTC | 80 | — | Administer 22% of empiric dose; dialysis 48 h after dose |
| Morrish (13) | 36 | PTC | 50, 120, 150, 250 over 4 y | 24–48 h | Use significantly larger 131I dose; first dialysis 48 h after dose |
| Magne (21) | 43 | PTC | 50 | 1, 3, 6 d | Increase dose up to 25% |
| Gallegos-Villalobos (22) | 51 | PTC | 100 | 1, 2 d; administer same dose with normal renal function | Administer same dose with normal renal function; use 2 subsequent dialysis sessions daily |
| 52 | PTC | 100 | |||
| Bhat (23) | 49 | PTC | 50 | 15, 27, 43 h | None |
*1 mCi = 37 MBq.
PTC = papillary thyroid carcinoma; VC = vesicular carcinoma; FTC = follicular thyroid carcinoma.