RT Journal Article SR Electronic T1 Rare Multisystem Histiocytic Sarcoma on 18F-FDG PET/CT JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP 358 OP 359 DO 10.2967/jnmt.121.262247 VO 49 IS 4 A1 Matthew Harwood A1 Fiona E. Craig A1 Ming Yang YR 2021 UL http://tech.snmjournals.org/content/49/4/358.abstract AB Histiocytic sarcoma (HS) is a rare malignancy with morphologic and immunophenotypic features indicating histiocytic differentiation. We present a case of HS with multisystem involvement, including an obstructing mass in the pancreatic head. 18F-FDG PET/CT is a valuable tool in staging this rare entity and in assessing the response to therapy. Knowing the diverse metastatic pattern of HS will help avoid imaging pitfalls on clinical 18F-FDG PET/CT scans.