PT - JOURNAL ARTICLE AU - Matthew Harwood AU - Fiona E. Craig AU - Ming Yang TI - Rare Multisystem Histiocytic Sarcoma on <sup>18</sup>F-FDG PET/CT AID - 10.2967/jnmt.121.262247 DP - 2021 Dec 01 TA - Journal of Nuclear Medicine Technology PG - 358--359 VI - 49 IP - 4 4099 - http://tech.snmjournals.org/content/49/4/358.short 4100 - http://tech.snmjournals.org/content/49/4/358.full SO - J. Nucl. Med. Technol.2021 Dec 01; 49 AB - Histiocytic sarcoma (HS) is a rare malignancy with morphologic and immunophenotypic features indicating histiocytic differentiation. We present a case of HS with multisystem involvement, including an obstructing mass in the pancreatic head. 18F-FDG PET/CT is a valuable tool in staging this rare entity and in assessing the response to therapy. Knowing the diverse metastatic pattern of HS will help avoid imaging pitfalls on clinical 18F-FDG PET/CT scans.