PT - JOURNAL ARTICLE AU - Robert M. Bober TI - Decay correction for quantitative myocardial PET perfusion in established PET scanners: a potentially overlooked source of errors AID - 10.2967/jnmt.121.262320 DP - 2021 Sep 01 TA - Journal of Nuclear Medicine Technology PG - jnmt.121.262320 4099 - http://tech.snmjournals.org/content/early/2021/09/27/jnmt.121.262320.short 4100 - http://tech.snmjournals.org/content/early/2021/09/27/jnmt.121.262320.full AB - Quantitative myocardial PET perfusion requires decay correction of the dynamic datasets to ensure measured activity reflects true physiology and not radiotracer decay or duration of frame intervals. Decay correction is typically performed by the PET camera system and the exact algorithm is buried within the settings and assumed to be correct for quantitative perfusion data. For quantitative myocardial perfusion, sequential dynamic images should be decay corrected to the activity at the mid time point of the first scan in the sequence. However, there are different decay correction algorithms that can be implemented depending on the needs and expertise of the laboratory. As such, prior to performing quantitative myocardial perfusion, testing the decay correction technique of a camera system should be performed.