PT  - JOURNAL ARTICLE
AU  - Julie Bolin
TI  - Thyroid Follicular Epithelial Cell–Derived Cancer: New Approaches and Treatment Strategies
AID  - 10.2967/jnmt.120.257105
DP  - 2021 Sep 01
TA  - Journal of Nuclear Medicine Technology
PG  - 199--208
VI  - 49
IP  - 3
4099  - http://tech.snmjournals.org/content/49/3/199.short
4100  - http://tech.snmjournals.org/content/49/3/199.full
SO  - J. Nucl. Med. Technol.2021 Sep 01; 49
AB  - Thyroid follicular epithelial cell–derived cancer includes papillary carcinoma, follicular carcinoma, Hürthle cell carcinoma, poorly differentiated thyroid cancer, and anaplastic thyroid carcinoma. Although the incidence of thyroid cancer has increased over the past 30 years, there has not been a significant increase in patient mortality. Use of increasingly sensitive detection methods such as high-resolution imaging has enabled earlier detection and better characterization of the thyroid malignancies. In the past several years, researchers have evaluated genetic mutations promoting thyroid carcinogenesis and oncogenesis. The identification of genetic mutations is important in understanding tumor initiation and progression. Additionally, these identified mutations may also serve as potential diagnostic or prognostic indicators and therapeutic molecular targets.