RT Journal Article SR Electronic T1 Interobserver Agreement in the Diagnosis of Parkinson Disease with Cardiac 123I-Metaiodobenzylguanidine Scintigraphy JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP 262 OP 264 DO 10.2967/jnmt.120.258632 VO 49 IS 3 A1 Robert W. Foley A1 Stewart L. Redman A1 Isabel J. Laurence A1 Richard N. Graham A1 David Little YR 2021 UL http://tech.snmjournals.org/content/49/3/262.abstract AB The aim of this study was to analyze the interobserver agreement of visual and quantitative assessment of cardiac 123I-metaiodobenzylguanidine scintigraphy. Methods: Planar images were acquired using a low-energy collimator. The heart-to-mediastinum (HM) ratio was adjusted for the use of a low-energy collimator, using a published formula. Interpretation was undertaken both visually and after the addition of adjusted HM ratios. Image findings were classified as normal, abnormal, or borderline. Results: The cohort consisted of 10 patients. On visual interpretation only, there was strong agreement on the interpretation of the scan (κ = 0.82, P < 0.01). Adjusted HM ratios led to a significant increase in mean ratios (1.79 vs. 1.36, P = 0.02) and, when utilized in reporting, resulted in perfect agreement (κ = 1.0, P < 0.01). Conclusion: The use of quantified HM ratios adjusted for low-energy collimator use improves on visual assessment alone and allowed for excellent interobserver agreement.