TY - JOUR T1 - U.S. Diagnostic Reference Levels and Achievable Administered Activities for Adult Renal Scintigraphy: An Analysis of the Intersocietal Accreditation Committee Nuclear Laboratories JF - Journal of Nuclear Medicine Technology JO - J. Nucl. Med. Technol. DO - 10.2967/jnmt.120.261552 SP - jnmt.120.261552 AU - Kevin P Banks AU - Rutger S. Gunther AU - Mary Beth Farrell AU - Justin G. Peacock AU - Maria Costello AU - Leonie Gordon Y1 - 2021/04/01 UR - http://tech.snmjournals.org/content/early/2021/04/02/jnmt.120.261552.abstract N2 - PURPOSE: The goal of this work was to determine U.S. diagnostic reference levels (DRLs) and achievable administered activities (AAAs) for adult renal scintigraphy. MATERIAL and METHODS: Under an Institutional Review Board approved protocol, data were collected from the Intersocietal Accreditation Commission (IAC) during one three-year accreditation cycle encompassing 110 facilities. Elements included radiopharmaceutical, administered activity, practice type, and examination volume. DRLs and AAAs were calculated and compared to non-US values and societal recommendations as available. RESULTS: 93 facilities provided data on to 99mTc mercaptuacetyltriglycine (MAG3) and 15 provided data on 99mTc diethylenetriaminepentaacetic acid (DTPA) for adult renal scintigraphy exams. Analysis demonstrated a DRL of 392.2 MBq (10.6 mCi) for MAG3 and 531.7 MBq (14.4 mCi) for DTPA, with an AAA of 370 MBq (10 mCi) for MAG3 and 445.9 MBq (12.1 mCi) for DTPA. CONCLUSION: The resultant calculated novel US DRLs and AAAs may serve as benchmarks that nuclear medicine facilities may use to refine renal scintigraphy protocols, reduce patient doses, and potentially guide future societal guideline recommendations. ER -