PT  - JOURNAL ARTICLE
AU  - Kenneth S. Zurcher
AU  - Odette M. Houghton
AU  - Joanne F. Shen
AU  - Mahesh Seetharam
AU  - Michael C. Roarke
AU  - Ming Yang
TI  - Nuclear Medicine and Molecular Imaging in Nodal Staging and Surveillance of Ocular Melanoma: Cases Report and Review of Literature
AID  - 10.2967/jnmt.120.260539
DP  - 2021 Apr 01
TA  - Journal of Nuclear Medicine Technology
PG  - jnmt.120.260539
4099  - http://tech.snmjournals.org/content/early/2021/04/02/jnmt.120.260539.short
4100  - http://tech.snmjournals.org/content/early/2021/04/02/jnmt.120.260539.full
AB  - Ocular melanoma (OM) is a rare noncutaneous malignancy and consists of 2 different subtypes based on anatomic location in the eye: uveal melanoma (UM) and conjunctival melanoma (CM). As in cutaneous melanoma, nuclear medicine and molecular imaging play valuable roles in the nodal staging and clinical management of OM. Through the illustration of 2 distinctive cases, we aim to demonstrate the complementary roles of standard lymphoscintigraphy, advanced single-photon emission computed tomography/computed tomography, 18F-fludeoxyglucose positron emission tomography/computed tomography, and hybrid positron emission tomography/magnetic resonance imaging in accurate nodal staging and surveillance of OM. We also review the epidemiology, existing staging guidelines and management of UM and CM.