PT - JOURNAL ARTICLE AU - Geoff M Currie AU - Peter Kamvosoulis AU - Stewart Bushong TI - PET/MR Part 2: Technological Principles AID - 10.2967/jnmt.120.261862 DP - 2021 Mar 01 TA - Journal of Nuclear Medicine Technology PG - jnmt.120.261862 4099 - http://tech.snmjournals.org/content/early/2021/03/12/jnmt.120.261862.short 4100 - http://tech.snmjournals.org/content/early/2021/03/12/jnmt.120.261862.full AB - The challenges of hybridizing position emission tomography (PET) and magnetic resonance imaging (MRI) as a simultaneous modality have been largely overcome in recent times. PET hybridized with magnetic resonance (MR) has seen the emergence of PET/MR imaging systems in the clinical setting and with it comes a responsibility to adapt appropriate facility design, safety practices, protocols and procedures, and clinical opportunity. This manuscript provides an insight into the considerations and challenges associated with PET/MR technology. Given the nature of PET is well established amongst the readership of this journal, the manuscript provides an introduction to the foundations of MRI instrumentation and emphasis on specific technological aspects of PET/MR systems. This manuscript is the second in a four-part integrated series sponsored by the SNMMI-TS PET/MR Task Force in conjunction with the SNMMI-TS Publication Committee; building on the previous article on establishing a facility (part 1). In subsequent editions, PET/MRI will be explored based on protocols and procedures (part 3), and applications and clinical cases (part 4).