RT Journal Article
SR Electronic
T1 Follicular thyroid carcinoma with unusual radioiodine refractory breast metastasis mimicking primary breast malignancy
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP jnmt.120.259259
DO 10.2967/jnmt.120.259259
A1 Tarun Kumar Jain
A1 Venkata Subramanian Krishnaraju
A1 Bhagwant Rai Mittal
A1 Ashwani Sood
A1 Rajender Kumar
A1 Rashi Garg
A1 Sunil Kumar
YR 2021
UL http://tech.snmjournals.org/content/early/2021/03/12/jnmt.120.259259.abstract
AB Breast is unusual site for metastasis from malignant tumors though may be the first manifestation of extra-mammary malignancy with primary typically arising from lung, melanoma, ovary and lymphoma. Breast metastasis is extremely rare from thyroid carcinoma and may take years to develop as differentiated thyroid carcinoma are usually indolent, slow growing and metastasize to lymph nodes, lungs and bones. Here is a middle-aged woman (post-subtotal thyroidectomy for multi-nodular goitre 24 years ago) showing discordant FDG and iodine avidity in proven metastatic disease involving lymph nodes, bones, spleen and breast on whole-body radioiodine and FDG-PET/CT due to tumor heterogeneity.