TY - JOUR T1 - Poorly differentiated Neuroendocrine carcinoma (small cell) of Parotid Gland and ‘Moderately differentiated’ Hepatic metastases: a Discordant Histopathology clarified by dual tracer PET-CT (<sup>68</sup>Ga-DOTATATE and <sup>18</sup>F-FDG) for predicting tumor biology and treatment decision-making JF - Journal of Nuclear Medicine Technology JO - J. Nucl. Med. Technol. DO - 10.2967/jnmt.120.251587 SP - jnmt.120.251587 AU - Priyanka Sharma AU - Sandip Basu Y1 - 2020/10/01 UR - http://tech.snmjournals.org/content/early/2020/10/02/jnmt.120.251587.abstract N2 - Metastatic neuroendocrine neoplasms (NEN) of the parotid gland, with discordant histopathology reports between primary parotid tumor (poorly differentiated small cell neuroendocrine carcinoma) and large hepatic metastasis (atypical carcinoid with moderately differentiation status, Ki-67 15-20%), and the value of dual tracer PET-CT imaging (68Ga-DOTATATE and 18F-FDG) features in such clinical setting are illustrated. Minimal 68Ga-DOTATATE and high grade 18FDG uptake of the lesions indicated a poor differentiation status helped in clarifying tumor biology, with its potential implications for subsequent treatment-decision individualization in favor of chemotherapy. The findings underscore the clinical utility of dual tracer PET-CT in appropriating the assessment in patients/situations with conflicting or discordant histopathology at two sites in an individual. ER -