RT Journal Article SR Electronic T1 Intervention to Lower Anxiety of 18F-FDG PET/CT Patients by Use of Audiovisual Imagery During the Uptake Phase Before Imaging JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP 92 OP 98 DO 10.2967/jnmt.111.097964 VO 40 IS 2 A1 Wouter V. Vogel A1 Renato A. Valdés Olmos A1 Tim J.W. Tijs A1 Murray F. Gillies A1 Gijs van Elswijk A1 Juergen Vogt YR 2012 UL http://tech.snmjournals.org/content/40/2/92.abstract AB Many patients referred for PET suffer from anxiety, possibly affecting the workflow and patient experience. In addition, patient anxiety may affect image quality through uptake of 18F-FDG in muscles or brown adipose tissue (BAT).This study investigated the effects of a nonpharmacologic intervention—the use of audiovisual imagery in the PET uptake room—on patient anxiety and false-positive uptake of 18F-FDG (in muscles and BAT). Methods: A 2-stage study was conducted on 101 patients. The cohort undergoing the intervention included 51 patients. The first stage (n = 35) included physiologic measurements (cardiovascular activity, muscular activity, skin conductance, and cortisol), a state anxiety questionnaire, and visual evaluation of 18F-FDG uptake in muscles and BAT; the second stage (n = 66) included only the state anxiety questionnaire and the 18F-FDG uptake evaluation. Results: Throughout the stay in the uptake room, a significant decrease in overall anxiety was found, together with several other significant changes in patient physiology. In the cohort with audiovisual intervention, however, the decrease in patient anxiety was significantly larger. The cohort with intervention also showed significantly lower 18F-FDG uptake in BAT but not in muscles. Conclusion: The investigated audiovisual intervention helps to lower patient anxiety in the PET uptake room and can lower false-positive 18F-FDG uptake in BAT.