PT  - JOURNAL ARTICLE
AU  - Tung, Kelly
AU  - Rosenthal, Allison C.
AU  - Craig, Fiona E.
AU  - Ashman, Jonathan B.
AU  - Yang, Ming
TI  - Pitfall of <sup>18</sup>F-FDG PET/CT in Characterization of Relapsed Multisystem Lymphomatoid Granulomatosis
AID  - 10.2967/jnmt.118.212274
DP  - 2018 Jun 01
TA  - Journal of Nuclear Medicine Technology
PG  - jnmt.118.212274
4099  - http://tech.snmjournals.org/content/early/2018/06/06/jnmt.118.212274.short
4100  - http://tech.snmjournals.org/content/early/2018/06/06/jnmt.118.212274.full
AB  - We present serial 18F-FDG PET/CT findings in a case of Epstein-Barr virus positive pulmonary lymphomatoid granulomatosis, grade 3. The patient experienced transient complete response to R-CHOP chemotherapy and subsequent multi-system recurrence, predominately involving the subcutaneous region of the torso on 18F-FDG PET/CT. Biopsy of the most hypermetabolic subcutaneous lesion demonstrated EBV negative cutaneous lymphomatoid granulomatosis, grade 1. This report highlights the role of 18F-FDG PET/CT in characterizing and monitoring disease progression and regression, as well as its limitation in accurate grading of multisystem recurrence given the diversity of clinical and histopathological feature of lymphomatoid granulomatosis.