RT Journal Article
SR Electronic
T1 Can Ga-68 DOTA Peptides be Potential Radiotracers for PET Imaging of Spleen?
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP jnmt.117.203448
DO 10.2967/jnmt.117.203448
A1 Ismet Sarikaya
A1 Abdelhamid Elgazzar
A1 Ali Sarikaya
A1 Naheel Alnafisi
A1 Saud Alenezi
YR 2018
UL http://tech.snmjournals.org/content/early/2018/03/29/jnmt.117.203448.abstract
AB On radionuclide somatostatin receptor (SSTR) imaging studies spleen shows very high uptake which is a physiological finding. Reducing intensity of the image settings helps to better assess the distribution of radiotracer in the spleen. In our routine studies we incidentally recognized that Gallium-68 (Ga-68) DOTANOC positron emission tomography (PET) provides higher resolution splenic images as compared to In-111 Octreotide single photon emission computed tomography (SPECT). Autoradiography and immunohistochemistry studies have shown that SSTRs are mainly located in the red pulp of the spleen. Distribution of Ga-68 DOTANOC in the spleen appears to be correlating with the distribution of red pulp. In this article we will present Ga-68 DOTANOC PET/CT spleen images of our patients.