TY - JOUR T1 - Occurrence of ‘Redifferentiation akin’ phenomenon on [<sup>68</sup>Ga]Ga-DOTATATE PET-CT following CAPTEM chemotherapy in Metastatic Neuroendocrine Tumours with intermediate MiB-1 index: what could be the molecular explanation? JF - Journal of Nuclear Medicine Technology JO - J. Nucl. Med. Technol. DO - 10.2967/jnmt.120.241539 SP - jnmt.120.241539 AU - Priyanka Sharma AU - Sandip Basu Y1 - 2020/02/01 UR - http://tech.snmjournals.org/content/early/2020/02/27/jnmt.120.241539.abstract N2 - In this report, we present the [68Ga]Ga-DOTATATE PET-CT images (pre- and post-chemotherapy) of a patient with intermediate grade metastatic neuroendocrine tumor (NET) with intermediate grade/Ki-67 index who had minimal somatostatin receptor positivity at baseline [68Ga]Ga-DOTATATE PET-CT, but had demonstrated high grade positivity on somatostatin receptor imaging (Krenning score III-IV) on follow-up scan after chemotherapy. This ‘redifferentiation-akin’ phenomenon in intermediate grade NETs following chemotherapy can have potential implications for the feasibility of peptide receptor radionuclide therapy (PRRT) in this group of patients in their course of disease at a later phase. ER -