PT  - JOURNAL ARTICLE
AU  - Ziessman, Harvey A
TI  - Sincalide - A review of the clinical utility, proper infusion methodology, and alternative cholecystogogues
AID  - 10.2967/jnmt.119.226019
DP  - 2019 Apr 01
TA  - Journal of Nuclear Medicine Technology
PG  - jnmt.119.226019
4099  - http://tech.snmjournals.org/content/early/2019/04/19/jnmt.119.226019.short
4100  - http://tech.snmjournals.org/content/early/2019/04/19/jnmt.119.226019.full
AB  - Sincalide (Kinevac®) is widely used in conjunction with cholescintigraphy for a variety of clinical indications. Over the years numerous publications have verified the optimal infusion methodology. Published data and consensus recommendations emphasize that sincalide 0.02 µg/kg should be infused over 60 minutes. Production problems sometimes limit the availability of sincalide. In that case, non-FDA pharmacy compounded sincalide may serve as an alternative. Fatty meals have also been used. Various illnesses and drugs may inhibit gallbladder contraction. Thus these drugs should be withheld for 48 hours prior to the study. Sincalide cholescintigraphy is most commonly used to diagnose or exclude chronic acalculous gallbladder disease. The study should preferably be performed as an outpatient.