PT  - JOURNAL ARTICLE
AU  - Mathieu Charest
AU  - Josephine Pressacco
AU  - Jaramie Thomas-Gittens
TI  - Malignant peripheral nerve sheath tumours of the pericardium in a patient with Neurofibromatosis type 1: The diagnostic value of 18F-FDG PET-CT and I-123 MIBG SPECT-CT
AID  - 10.2967/jnmt.117.199927
DP  - 2017 Nov 01
TA  - Journal of Nuclear Medicine Technology
PG  - jnmt.117.199927
4099  - http://tech.snmjournals.org/content/early/2017/11/08/jnmt.117.199927.short
4100  - http://tech.snmjournals.org/content/early/2017/11/08/jnmt.117.199927.full
AB  - A 25 year old female with known neurofibromatosis type 1 with a large anterior mediastinal mass was investigated. F18-FDG PET-CT revealed a radiotracer avid anterior mediastinal mass with SUVmax of 4.3 and demonstrating a hypoactive center. The Iodine-123 MIBG SPECT-CT study performed subsequently did not demonstrate any uptake, thereby excluding for the most part the diagnoses of paraganglioma or neuroblastoma. At final pathology, a malignant peripheral nerve sheath tumour (MPNST) of the pericardium with areas of chondrosarcomatous and angiosarcomatous differentiation was diagnosed.