RT Journal Article SR Electronic T1 Validation of an ergonomic method to withdraw [99mTc] radiopharmaceuticals JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP jnmt.117.199133 DO 10.2967/jnmt.117.199133 A1 BLONDEEL-GOMES, Sandy A1 MARIE, Solène A1 FOUQUE, Julien A1 LOYEAU, Sabrina A1 MADAR, Olivier A1 LOKIEC, François YR 2017 UL http://tech.snmjournals.org/content/early/2017/11/08/jnmt.117.199133.abstract AB The main objective of the present work was to ensure quality of radiopharmaceuticals syringes withdrawn with a “Spinal needle/obturator In-Stopper” system. Methods: Visual examinations and physicochemical tests are performed at T0 and T+4h for [99mTc]albumin nanocolloid and T+7h for [99mTc]eluate, [99mTc] HydroxyMethylene DiPhosphonate and [99mTc]Human Serum Albumin. Microbiological validation was performed according to European pharmacopoeia. Fingertip radiation exposure was evaluated to confirm the safety of the system. Results: Results show stable visual and physicochemical properties. The integrity of the connector was not affected after 30 punctures (no cores). No microbiological contamination was found on tested syringes. Conclusion: The system could be used 30 times. The stability of syringes drawing with this method is guaranteed up to 4 hours for [99mTc]albumin nanocolloid and 7 hours for [99mTc]eluate, [99mTc]HydroxyMethylene DisPhosphonate and [99mTc]Human serum albumin.