RT Journal Article
SR Electronic
T1 Aggressive Clinical Course of Dermatofibrosarcoma protuberans: <sup>18</sup>F-FDG PET-CT predictive of Tumor Biology
JF Journal of Nuclear Medicine Technology
JO J. Nucl. Med. Technol.
FD Society of Nuclear Medicine
SP jnmt.115.163212
DO 10.2967/jnmt.115.163212
A1 BASU, SANDIP
A1 Goliwale, Fahim
YR 2015
UL http://tech.snmjournals.org/content/early/2015/09/02/jnmt.115.163212.abstract
AB Assessment of tumor biology is an added aspect of molecular imaging with 18F-FDG PET/CT, which scores over the conventional anatomical imaging in malignancies. An unusual and aggressive case of Dermatofibrosarcoma Protuberans (DFSP) with fatal disease course is presented. In the present case, the high grade 18F-FDG uptake in the DFSP lesions was predictive of an aggressive disease course in this otherwise indolent behaving entity. The aggressive clinical course was unabated by tyrosine kinase inhibitor imatinib mesylate and the patient showed poor response to this therapy.